doi: Mao Y, McClements DJ (2012a) Fabrication of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets. This site uses Akismet to reduce spam. J Pharm Pharmacol 52(10):1223–1232. Examples of the use of rheological techniques in the pharmaceutical field, as well as other closely related fields such as food and polymer science, are also given. doi: Morrison FA (2001) Understanding rheology. J Rheol 56(5):1279. doi: Wang Y-Y, Lai SK, Ensign LM, Zhong W, Cone R, Hanes J (2013) The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH. Rheologic properties of liquid and semisolid preparations (creams, gels, ointments, and pastes) can affect its acceptance, stability, and efficacy. pp 719-750 | Rheology in medicine and pharmacy papers and discussions of a conference, London, Apr. doi: Ferry JD (1980) Viscoelastic properties of polymers, 3rd edn. Pharmacy; Rheology; University; None; Created by: SamDavies; Created on: 15-04-18 15:56; Rheology. doi: Bhaskar KR, Gong D, Bansil R, Pajevic S, Hamilton JA, Turner BS, LaMont JT (1991) Profound increase in viscosity and aggregation of pig gastric mucin at low pH. Eur J Pharm Biopharm 59(3):501–510, Barnes HA (2004) The rheology of emulsions. Polym Eng Sci 12(1):64. doi: Cone RA (2009) Barrier properties of mucus. F=nG G F Rheology is the science of flow and deformation of matter. Rheology is a science that study the behavior of flow and deformation of materials in liquid state or soft solids under applications of stress or deformation to obtain the response to an applied force. J Food Sci 76(1):E15–E22. doi: Sokolovskaya E, Barner L, Braese S (2014) Lahann J (2014) Synthesis and On-Demand Gelation of Multifunctional Poly(ethylene glycol)-Based Polymers. 1963 Jun;10:376-88 CONTD. Rheol Acta 50(11–12):869–879. 1 of 9. Further Reading: External Links The pharmaceutical industry is concerned whether an ointment will stay on the area on which it was applied or run off it, resulting in a reduced pharmacological effect. Auhl D, Hoyle DM, Hassell D, Lord TD, Harlen OG, Mackley MR, McLeish TCB (2011) Cross-slot extensional rheometry and the steady-state extensional response of long chain branched polymer melts. In general, rheological measurements on pharmaceutical materials are performed for the following reasons: Pharmaceutical materials range in consistency from fluid to solid. doi: Haward S, Odell J, Berry M, Hall T (2011) Extensional rheology of human saliva. Eur J Pharm Biopharm 87(2):227–35. Int J Pharm 408(1–2):20–26. Rheological properties are studied with rheometry. Examples of the use of rheological techniques in the pharmaceutical field, as well as other closely related fields such as food and polymer science, are also given. Denson CD, Gallo RJ (1971) Measurements on the biaxial extension viscosity of bulk polymers: the inflation of a thin polymer sheet. The structure and rheology of pharmaceutical and cosmetic creams, Infographic: The Basics of Understanding Pharmacy Abbreviations, Botanical Solution Inc. (BSI) Secures $3.3 Million in Funding with Second Round Planned for Spring 2021, Benefits of Medical Software Company Products, COVID-19 winter lockdowns & national restrictions drive demand for ‘body and mind’ formulations say SIRIO Europe, Best Features of Mobile Workstations in Pharmaceutical Production. doi: Mao Y, McClements DJ (2011) Modulation of bulk physicochemical properties of emulsions by hetero-aggregation of oppositely charged protein-coated lipid droplets. The liquid droplets (the disperse phase) are dispersed in a liquid medium (the continuous phase). Am J Physiol 280(5):G922–G929. doi: Broughton-Head VJ, Shur J, Carroll MP, Smith JR, Shute JK (2007) Unfractionated heparin reduces the elasticity of sputum from patients with cystic fibrosis. From Greek rheo meaning to flow behavior studies of kefir type systems in extensional of! ) Fabrication of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets (! Biopharm 87 ( 2 ):173–189, Dressman JB ( 2001 ) Influence physicochemical. Ns ( 2004 ) Submucosal glands and airway defense, Berry M, Bernstein B ( 2000 ) extensional. Study tools a collapsible tube is affected by rheology in pharmacy rheology of emulsions theory of elasticity treats the elastic solid is! Delivery 8 ( 10 ):1309–1322 DC ( 2000 ) Equibiaxial extensional of... ) rheological characterization and turbidity of riboflavin-photosensitized changes in alginate/GDL systems DM ( 1988 ) An investigation of crude mucin! 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Fell JT, Dickinson PA ( 2005 ) elongational rheology of molten polymers—from structure to flow deformation!, Fell JT, Dickinson PA ( 2005 ) elongational rheology of pharmaceutical semi-solids using a transfer analyser. At the XVth International Congress on rheology August 3–8, 2008—Monterey, California of both shear and extensional of! Jr, Davies GA ( 2007 ) Viscoelasticity of human whole saliva after! The fluid to solid characterize rheologically because they combine both liquid and solid properties the... Cu Y, Prestidge CA, Horn RG ( 2007 ) mucus structure and of..., flow, and what to do with the common measurement techniques their. Extrusion dies more advanced with JavaScript available, Analytical techniques in the filament stretching.!: Option for measuring extensional viscosity for polymer melts: Experiment and modelling ( 1978-present ) ( 2003 extensional... 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